Dna replication steps
- explain how proteins assist in dna replication
- how are proteins involved in dna replication
- what are the proteins and enzymes involved in dna replication
- what roles do proteins play in dna replication
Dna replication pdf...
Dna replication process
Enzymes and proteins involved in DNA replication
A number of enzymes and proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis, Most prominently, DNA polymerase synthesizes the new strands by adding nucleotides that complement each (template) strand.
DNA replication occurs during the S-phase of interphase.
At the replication fork, many replication enzymes assemble on the DNA into a complex molecular machine called the replisome. The following is a list of major DNA replication enzymes that participate in the replisome.
1) DNA Helicase :
- Helicase enzyme opens up the DNA double helix by breakinghydrogen bond between two strands of DNA and provide single template strand.
- DNA-B is a primary replicative Helicase it binds and moveonlagging strand in 5' to 3' direction unwinding the duplex as it goes.
- Helicase requires ATP as energy source
2) Single Stranded Binding Proteins (SSB proteins) :
- SSB proteins binds to both seperated single stranded DNA and preve
- explain how dna is used to make a protein
- explain how a protein comes from dna